Paediatric Respiratory Reviews
Volume 6, Issue 4 , Pages 246-254 , December 2005

Forced oscillation technique in infants and young children

  • Urs Frey

      Affiliations

    • Corresponding Author InformationTel.: +41 31 632 93 94; fax: +41 31 632 94 84.

References 

  1. Oostveen E, MacLeod D, Lorino H, et al. The forced oscillation technique in clinical practice: methodology, recommendations and future developments. Eur Respir J. 2003;22:1026–1041
  2. Marchal F, Davis M, Ducharme FM, Hall GL, Hantos Z, Oostveen E. The ATS/ERS working group on infant and young children pulmonary function testing: The forced oscillation technique in preschool children: recommendations. Submitted for publication.
  3. DuBois AB, Brody AW, Lewis DH, Burgess BF. Oscillation mechanics of lungs and chest in man. J Appl Physiol. 1956;8:587–594
  4. Hantos Z, Daroczy B, Suki B, Galgoczy G, Csendes T. Forced oscillatory impedance of the respiratory system at low frequencies. J Appl Physiol. 1986;60:123–132
  5. Sly PD, Hayden MJ, Petak F, Hantos Z. Measurement of low-frequency respiratory impedance in infants. Am J Respir Crit Care Med. 1996;154:161–166
  6. Pillow JJ, Stocks J, Sly PD, Hantos Z. Partitioning of airway and parenchymal mechanics in unsedated newborn infants. Ped Res. 2005;in press
  7. Hantos Z, Daroczy B, Csendes T, Suki B, Nagy S. Modeling of low-frequency pulmonary impedance in dogs. J Appl Physiol. 1990;68:849–860
  8. Hantos Z, Daroczy B, Suki B, Nagy S, Fredberg JJ. Input impedance and peripheral inhomogeneity of dog lungs. J Appl Physiol. 1992;72:168–178
  9. Jackson AC, Giurdanella CA, Dorkin HL. Density dependence of respiratory system impedances between 5 and 320 Hz in humans. J Appl Physiol. 1989;67:2323–2330
  10. Vogel J, Schmidt U. Analysis of lung mechanics in general practice and the clinic, epidemiological and experimental research. Frankfurt, Pmi Verlagsgruppe GmbH 1994.
  11. Frey U, Suki B, Kraemer R, Jackson AC. Human respiratory input impedance between 32 and 800 Hz, measured by interrupter technique and forced oscillations. J Appl Physiol. 1997;82:1018–1023
  12. Frey U, Silverman M, Kraemer R, Jackson AC. High-frequency respiratory input impedance measurements in infants assessed by the high speed interrupter technique. Eur Respir J. 1998;12:148–158
  13. Jackson AC, Lutchen KR. Physiological basis for resonant frequencies in respiratory system impedances in dogs. J Appl Physiol. 1991;70:1051–1058
  14. Jackson AC, Tennhoff W, Kraemer R, Frey U. Airway and tissue resistance in wheezy infants: effects of albuterol. Am J Respir Crit Care Med. 1999;160:557–563
  15. Williams SP, Fullton JM, Tsai MJ, Pimmel RL, Collier AM. Respiratory impedance and derived parameters in young children by forced random noise. J Appl Physiol. 1979;47:169–174
  16. Stanescu D, Moavero NE, Veriter C, Brasseur L. Frequency dependence of respiratory resistance in healthy children. J Appl Physiol. 1979;47:268–272
  17. Hantos Z, Daroczy B, Gyurkovits K. Total respiratory impedance in healthy children. Pediatr Pulmonol. 1985;1:91–98
  18. Solymar L, Aronsson PH, Bake B, Bjure J. Respiratory resistance and impedance magnitude in healthy children aged 2–18 years. Pediatr Pulmonol. 1985;1:134–140
  19. Duiverman EJ, Clement J, van de Woestijne KP, Neijens HJ, van den Bergh AC, Kerrebijn KF. Forced oscillation technique. Reference values for resistance and reactance over a frequency spectrum of 2–26Hz in healthy children aged 2. 3–12. 5 years. Bull Eur Physiopathol Respir. 1985;21:171–178
  20. Lebecque P, Desmond K, Swartebroeckx Y, Dubois P, Lulling J, Coates A. Measurement of respiratory system resistance by forced oscillation in normal children: a comparison with spirometric values. Pediatr Pulmonol. 1991;10:117–122
  21. Hellinckx J, De Boeck K, Bande-Knops J, van der Poel M, Demedts M. Bronchodilator response in 3–6.5 years old healthy and stable asthmatic children. Eur Respir J. 1998;12:438–443
  22. Hordvik NL, Konig P, Morris DA, Kreutz C, Pimmel RL. Normal values for forced oscillatory respiratory resistance in children. Pediatr Pulmonol. 1985;1:145–148
  23. Ducharme FM, Davis GM, Ducharme GR. Pediatric reference values for respiratory resistance measured by forced oscillation. Chest. 1998;113:1322–1328
  24. Lierl MB, Hilman BC. Normal values for forced oscillation parameters in small children. J Asthma. 1986;23:179–185
  25. Solymar L, Aronsson PH, Engstrom I, Bake B, Bjure J. Forced oscillation technique and maximum expiratory flows in bronchial provocation tests in children. Eur J Respir Dis. 1984;65:486–495
  26. Timonen KL, Randell JT, Salonen RO, Pekkanen J. Short-term variations in oscillatory and spirometric lung function indices among school children. Eur Respir J. 1997;10:82–87
  27. Buhr W, Jorres R, Berdel D, Landser FJ. Correspondence between forced oscillation and body plethysmography during bronchoprovocation with carbachol in children. Pediatr Pulmonol. 1990;8:280–288
  28. Lenney W, Milner AD. At what age do bronchodilator drugs work?. Arch Dis Child. 1978;53:532–535
  29. Delacourt C, Lorino H, Herve-Guillot M, Reinert P, Harf A, Housset B. Use of the forced oscillation technique to assess airway obstruction and reversibility in children. Am J Respir Crit Care Med. 2000;161:730–736
  30. Desager KN, Buhr W, Willemen M, et al. Measurement of total respiratory impedance in infants by the forced oscillation technique. J Appl Physiol. 1991;71:770–776
  31. Frey U, Silverman M, Kraemer R, Jackson AC. High-frequency respiratory impedance measured by forced-oscillation technique in infants. Am J Respir Crit Care Med. 1998;158:363–370
  32. Hall GL, Hantos Z, Wildhaber JH, Petak F, Sly PD. Methacholine responsiveness in infants assessed with low frequency forced oscillation and forced expiration techniques. Thorax. 2001;56:42–47
  33. Delacourt C, Lorino H, Fuhrman C, et al. Comparison of the forced oscillation technique and the interrupter technique for assessing airway obstruction and its reversibility in children. Am J Respir Crit Care Med. 2001;164:965–972
  34. Cauberghs M, Van de Woestijne KP. Effect of upper airway shunt and series properties on respiratory impedance measurements. J Appl Physiol. 1989;66:2274–2279
  35. Marchal F, Haouzi P, Peslin R, Duvivier C, Gallina C. Mechanical properties of the upper airway wall in children and their influence on respiratory impedance measurements. Pediatr Pulmonol. 1992;13:28–33
  36. Peslin R, Duvivier C, Didelon J, Gallina C. Respiratory impedance measured with head generator to minimise upper airway shunt. J Appl Physiol. 1985;59:1790–1795
  37. Marchal F, Mazurek H, Habib M, Duvivier C, Derelle J, Peslin R. Input respiratory impedance to estimate airway hyperreactivity in children: standard method versus head generator. Eur Respir J. 1994;7:601–607
  38. Marchal F, Peslin R, Duvivier C, Gallina C, Crance JP. Measurement of ventilatory mechanical impedance in infants using a head pressure generator. Pediatr Pulmonol. 1989;7:209–216
  39. Mazurek H, Willim G, Marchal F, Haluszka J, Tomalak W. Input respiratory impedance measured by head generator in preschool children. Pediatr Pulmonol. 2000;30:47–55
  40. Marchal F, Bouaziz N, Baeyert C, Gallina C, Duvivier C, Peslin R. Separation of airway and tissue properties by transfer respiratory impedance and thoracic gas volume in reversible airway obstruction. Eur Respir J. 1996;9:253–261
  41. Farre R, Rotger M, Marchal F, Peslin R, Navajas D. Assessment of bronchial reactivity by forced oscillation admittance avoids the upper airway artefact. Eur Respir J. 1999;13:761–766
  42. Hall GL, Hantos Z, Petak F, et al. Airway and respiratory tissue mechanics in normal infants. Am J Respir Crit Care Med. 2000;162:1397–1402
  43. Lutchen KR, Suki B, Zhang Q, Petak F, Daroczy B, Hantos Z. Airway and tissue mechanics during physiological breathing and bronchoconstriction in dogs. J Appl Physiol. 1994;77:373–385
  44. Cuijpers CE, Wesseling G, Swaen GM, Wouters EF. Frequency dependence of oscillatory resistance in healthy primary school children. Respiration. 1993;60:149–154
  45. Desager KN, Cauberghs M, Naudts J, van de Woestijne KP. Influence of upper airway shunt on total respiratory impedance in infants. J Appl Physiol. 1999;87:902–909
  46. Klug B, Bisgaard H. Specific airway resistance, interrupter resistance and respiratory impedance in healthy children aged 2-7 years. Pediatr Pulmonol. 1998;25:322–331
  47. Klug B, Bisgaard H. Measurement of lung function in awake 2-4-year-old asthmatic children during methacholine challenge and acute asthma: a comparison of the impulse oscillation technique, the interrupter technique and transcutaneous measurement of oxygen versus whole-body plethysmography. Pediatr Pulmonol. 1996;21:290–300
  48. Jackson AC, Neff KM, Dorkin HL, Lutchen KR. Interpretation of respiratory input impedance in healthy infants. Pediatr Pulmonol. 1996;22:364–375
  49. Frey U, Makkonen K, Wellman T, Beardsmore C, Silverman M. Alterations in airway wall properties in infants with a history of wheezing disorders. Am J Respir Crit Care Med. 2000;161:1825–1829
  50. Henschen M, Stocks J, Brookes I, Frey U. New aspects of airway mechanics in preterm infants. Eur Resp J. 2003;22;Suppl 45, A857
  51. Habib RH, Chalker RB, Suki B, Jackson AC. Airway geometry and wall mechanical properties estimated from subglottal input impedance in humans. J Appl Physiol. 1994;77:441–451
  52. Jackson AC, Suki B, Ucar M, Habib R. Branching airway network models for analyzing high-frequency lung input impedance. J Appl Physiol. 1993;75:217–227
  53. Cogswell JJ. Forced oscillation technique for determination of resistance to breathing in children. Arch Dis Child. 1973;48:259–266
  54. Lebecque P, Stanescu D. Respiratory resistance by the forced oscillation technique in asthmatic children and cystic fibrosis patients. Eur Respir J. 1997;10:891–895
  55. Holmgren D, Engstrom I, Bjure J, Sixt R, Aberg N. Respiratory resistance and transcutaneous PO2 during histamine provocation in children with bronchial asthma. Pediatr Pulmonol. 1993;15:168–174
  56. Ducharme FM, Davis GM. Respiratory resistance in the emergency department: a reproducible and responsive measure of asthma severity. Chest. 1998;113:1566–1572
  57. Ducharme FM, Davis GM. Measurement of respiratory resistance in the emergency department: feasibility in young children with acute asthma. Chest. 1997;111:1519–1525
  58. Chalut DS, Ducharme FM, Davis GM. The Preschool Respiratory Assessment Measure (PRAM): a responsive index of acute asthma severity. J Pediatr. 2000;137:762–768
  59. Duiverman EJ, Neijens HJ, van Strik R, van der Snee-van Smaalen M, Kerrebijn KF. Bronchial responsiveness in asthmatic children aged 3 to 8 years measured by forced pseudo-random noise oscillometry. Bull Eur Physiopathol Respir. 1986;22:27–33
  60. Duiverman EJ, Neijens HJ, Van der Snee-van Smaalen M, Kerrebijn KF. Comparison of forced oscillometry and forced expirations for measuring dose-related responses to inhaled methacholine in asthmatic children. Bull Eur Physiopathol Respir. 1986;22:433–436
  61. Lebecque P, Spier S, Lapierre JG, Lamarre A, Zinman R, Coates AL. Histamine challenge test in children using forced oscillation to measure total respiratory resistance. Chest. 1987;92:313–318
  62. Wilson NM, Bridge P, Phagoo SB, Silverman M. The measurement of methacholine responsiveness in 5 year old children: three methods compared. Eur Respir J. 1995;8:364–370
  63. Bouaziz N, Beyaert C, Gauthier R, Monin P, Peslin R, Marchal F. Respiratory system reactance as an indicator of the intrathoracic airway response to methacholine in children. Pediatr Pulmonol. 1996;22:7–13
  64. Ortiz G, Menendez R. The effects of inhaled albuterol and salmeterol in 2- to 5-year-old asthmatic children as measured by impulse oscillometry. J Asthma. 2002;39:531–536
  65. Nielsen KG, Bisgaard H. Discriminative capacity of bronchodilator response measured with three different lung function techniques in asthmatic and healthy children aged 2 to 5 years. Am J Respir Crit Care Med. 2001;164:554–559
  66. Nielsen KG, Bisgaard H. Bronchodilation and bronchoprotection in asthmatic preschool children from formoterol administered by mechanically actuated dry-powder inhaler and spacer. Am J Respir Crit Care Med. 2001;164:256–259
  67. Nielsen KG, Bisgaard H. The effect of inhaled budesonide on symptoms, lung function and cold air and methacholine responsiveness in 2- to 5-year-old asthmatic children. Am J Respir Crit Care Med. 2000;162:1500–1506
  68. Nielsen KG, Bisgaard H. Lung function response to cold air challenge in asthmatic and healthy children of 2-5 years of age. Am J Respir Crit Care Med. 2000;161:1805–1809
  69. Frey U. Effects of deep inhalations on bronchial reactivity in pediatric asthma. Pediatr Pulmonol. 2002;33:409–410
  70. Marchal F, Schweitzer C, Moreau-Colson C. Respiratory impedance response to a deep inhalation in children with history of cough or asthma. Pediatr Pulmonol. 2002;33:411–418
  71. Schweitzer C, Moreau-Colson C, Marchal F. Respiratory impedance response to a deep inhalation in asthmatic children with spontaneous airway obstruction. Eur Respir J. 2002;19:1020–1025
  72. Loring SH, Ingram RH, Drazen JM. Effects of lung inflation on airway and tissue responses to aerosol histamine. J Appl Physiol. 1981;51:806–811
  73. Hayden MJ, Petak F, Hantos Z, Hall G, Sly PD. Using low-frequency oscillation to detect bronchodilator responsiveness in infants. Am J Respir Crit Care Med. 1998;157:574–579
  74. Hall GL, Hantos Z, Sly PD. Altered respiratory tissue mechanics in asymptomatic wheezy infants. Am J Respir Crit Care Med. 2001;164:1387–1391
  75. Frey U, Jackson AC, Silverman M. Differences in airway wall compliance as a possible mechanism for wheezing disorders in infants. Eur Respir J. 1998;12:136–142
  76. Chalker RB, Celli BR, Habib RH, Jackson AC. Respiratory input impedance from 4 to 256Hz in normals and chronic airflow obstruction: comparisons and correlations with spirometry. Am Rev Respir Dis. 1992;146:570–576
  77. Solymar L, Aronsson PH, Sixt R. The forced oscillation technique in children with respiratory disease. Pediatr Pulmonol. 1985;1:256–261
  78. Hellinckx J, De Boeck K, Demedts M. No paradoxical bronchodilator response with forced oscillation technique in children with cystic fibrosis. Chest. 1998;113:55–59
  79. Nielsen KG, Pressler T, Klug B, Koch C, Bisgaard H. Serial lung function and responsiveness in cystic fibrosis during early childhood. Am J Respir Crit Care Med. 2004;169:1209–1216
  80. Brennan S, Hall GL, Horak F, et al. Correlation of forced oscillation technique in preschool children with cystic fibrosis with pulmonary inflammation. Thorax. 2005;60:159–163
  81. Dorkin HL, Stark AR, Werthammer JW, Strieder DJ, Fredberg JJ, Frantz ID. Respiratory system impedance from 4 to 40 Hz in paralyzed intubated infants with respiratory disease. J Clin Invest. 1983;72:903–910
  82. Malmberg LP, Mieskonen S, Pelkonen A, Kari A, Sovijarvi AR, Turpeinen M. Lung function measured by the oscillometric method in prematurely born children with chronic lung disease. Eur Respir J. 2000;16:598–603
  83. Udomittipong K, Hall GL, Patterson H, Gangell C, Stick SM, Sly PD. Preschool children with neonatal chronic lung disease exhibit altered lung function using forced oscillation. Respirology Vol 10: Supplement March 2005: A76.
  84. Lanteri CJ, Kano S, Duncan AW, Sly PD. Changes in respiratory mechanics in children undergoing cardiopulmonary bypass. Am J Respir Crit Care Med. 1995;152:1893–1900
  85. Wohl ME, Stigol LC, Mead J. Resistance of the total respiratory system in healthy infants and infants with bronchiolitis. Pediatrics. 1969;43:495–509
  86. Marchal F, Haouzi P, Gallina C, Crance JP. Measurement of ventilatory system resistance in infants and young children. Respir Physiol. 1988;73:201–209
  87. Lenney W, Milner AD. Recurrent wheezing in the preschool child. Arch Dis Child. 1978;53:468–473
  88. Frey U, Kraemer R. Oscillatory pressure transients after flow interruption during bronchial challenge test in children. Eur Respir J. 1997;10:75–81
  89. Que CL, Kenyon CM, Olivenstein R, Macklem PT, Maksym GN. Homeokinesis and short-term variability of human airway caliber. J Appl Physiol. 2001;91:1131–1141

PII: S1526-0542(05)00091-6

doi: 10.1016/j.prrv.2005.09.010

Paediatric Respiratory Reviews
Volume 6, Issue 4 , Pages 246-254 , December 2005

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